Clinical Evaluation of Shampoo Containing 0.75% Miconazole Nitrate for Dandruff.
نویسندگان
چکیده
منابع مشابه
Evaluation of the clinical efficacy and safety of “Anti-Dandruff Shampoo” in the treatment of dandruff
Dandruff (Pityriasis simplex) is a common embarrassing scalp disorder, affecting a large chunk of population. The yeast, Pityrosporum ovale is the causative microorganism of dandruff and due to its lipase activity it releases proinflammatory free fatty acids, causing dermal inflammation and tissue damage. Currently available treatment options have various limitations, either due to poor clinica...
متن کاملFormulation and Evaluation of Bioadhesive Vaginal Suppositories Containing Miconazole Nitrate
Miconazole nitrate is an imidazole derivative antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. Over 90% of miconazole nitrate is reported to be bound to plasma proteins. In this study, miconazole nitrate was formulated into bioadhesive vaginal suppositories using different suppository bases such as fat...
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The potential for boosting zinc pyrithione (ZPT) efficacy by using Zemea biobased propanediol in a generic dandruff shampoo formulation was evaluated in this study. A time-dependent, doseresponse relationship was observed between the mortality of Malassezia globosa, a microorganism associated with human dandruff, and Zemea concentration over a range of 0% to 4%. Formulation used in test solutio...
متن کاملIsolation of llama antibody fragments for prevention of dandruff by phage display in shampoo.
As part of research exploring the feasibility of using antibody fragments to inhibit the growth of organisms implicated in dandruff, we isolated antibody fragments that bind to a cell surface protein of Malassezia furfur in the presence of shampoo. We found that phage display of llama single-domain antibody fragments (VHHs) can be extended to very harsh conditions, such as the presence of shamp...
متن کاملSolubility Enhancement of Miconazole Nitrate for Formulation and Evaluation of Mucoadhesive Gel
The goal of the present investigation is formulation and evaluation of a mucoadhesive gel for buccal delivery after solubility enhancement of very slightly water-soluble drug Miconazole Nitrate. Miconazole Nitrate is imidazole derivative useful in treatment of oropharyngeal Candidiasis, the most common infection in AIDS patients. The method namely solvent deposition with inclusion complex, soli...
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ژورنال
عنوان ژورنال: Nippon Ishinkin Gakkai Zasshi
سال: 1997
ISSN: 0916-4804,1882-0476
DOI: 10.3314/jjmm.38.99